ABC reports that a Northern California company, Revance Therapeutics, is already in Phase 3 trials, testing a topical method for administering botulinum toxin for the treatment of crow’s-feet. Its gel formula allows the ingredient to travel through the skin using peptides to deliver the wrinkle-smoothing benefits. Not only do the before-and-after photos look very convincing, but so far, the study shows results lasting twice as long as the three month period that neuromodulators such as Botox, Dysport and Xeomin provide.

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